To minimize adverse side effects and potential harmful drug interactions, it is important for the team of patient, physician and pharmacist to be mindful about benefit-risk analysis.  studies have shown that slower titration at lower doses have a marked reduction in adverse events while also improving the therapeutic efficacy of the medical cannabis. A “low and slow” dosing protocol, starting with low THC and higher CBD content and utilizing quarterly cannabis detoxes, is the most appropriate protocol for most medical cannabis patients.

Patients should refrain from driving or operating heavy machinery for at least three hours after consuming inhaled cannabis or at least eight hours after consuming cannabis orally. Patients should be mindful that cannabis can increase the effects of prescribed opiate painkillers and pharmaceuticals that may cause drowsiness. Cannabis may act synergistically with alcohol (increasing the effects of the cannabis and alcohol), so alcohol should not be consumed for at least three hours after consuming inhaled cannabis or eight hours after consuming cannabis orally. Cannabis should not be used while still under the effects of alcohol. Patients should consult a medical or cannabis professional for additional guidance regarding other prescription drug interactions and cannabis medicine.

To read more about the low and slow dosing protocol purchase Cannabis Primer: An Introduction to Cannabis for Consumers, Producers, Providers, Policy Makers, and Health Professionals